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GSK620
- 英文名称:GSK620
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11088
- cas:2088410-46-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11088 |
用途 | 科研检测 |
英文名称 | GSK620 |
包装规格 | 1MG |
CAS编号 | 2088410-46-0 |
别名 | GSK620 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C18H19N3O3
分子量:325.37
溶剂:DMSO (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):BD2 selective BET inhibitor
Function / Pharmacology:BET inhibitor 220-fold more selective for BD2 over BD1 (pIC50 BD2 = 7.1; BD1 = 4.8).1 It ameliorated collagen-induced arthritis in a rat model and imiquimod-induced psoriasis in a mouse model.2 GSK620 was also able to reduce hepatic fibrosis, steatosis, and inflammation in a mouse model of non-alcoholic steatohepatitis (NASH).
分子式:C18H19N3O3
分子量:325.37
溶剂:DMSO (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):BD2 selective BET inhibitor
Function / Pharmacology:BET inhibitor 220-fold more selective for BD2 over BD1 (pIC50 BD2 = 7.1; BD1 = 4.8).1 It ameliorated collagen-induced arthritis in a rat model and imiquimod-induced psoriasis in a mouse model.2 GSK620 was also able to reduce hepatic fibrosis, steatosis, and inflammation in a mouse model of non-alcoholic steatohepatitis (NASH).