|
P053
- 英文名称：P053
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11094
- cas：1022417-69-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11094 |
| 用途 | 科研检测 |
| 英文名称 | P053 |
| 包装规格 | 1MG |
| CAS编号 | 1022417-69-1 |
| 别名 | P053 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C18H18N2O3S
分子量:342.41
溶剂:DMSO (>50 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):Protein phosphatase 5 inhibitor
Function / Pharmacology:P053 is a selective inhibitor of protein phosphatase 5 (PP5) – IC50 = 706 nM.1 PP5 regulates signaling cascades that are responsible for tumor initiation, progression, and metastasis and is thus an interesting anticancer target. P053 induced apoptosis in 786-O renal carcinoma cells. Inhibition of PP5 by P053 prevents deactivation of the death effector protein FADD and activates the extrinsic apoptosis pathway complex II.
分子式:C18H18N2O3S
分子量:342.41
溶剂:DMSO (>50 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):Protein phosphatase 5 inhibitor
Function / Pharmacology:P053 is a selective inhibitor of protein phosphatase 5 (PP5) – IC50 = 706 nM.1 PP5 regulates signaling cascades that are responsible for tumor initiation, progression, and metastasis and is thus an interesting anticancer target. P053 induced apoptosis in 786-O renal carcinoma cells. Inhibition of PP5 by P053 prevents deactivation of the death effector protein FADD and activates the extrinsic apoptosis pathway complex II.
