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A-438079 HCl
- 英文名称:A-438079 HCl
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11095
- cas:899431-18-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11095 |
用途 | 科研检测 |
英文名称 | A-438079 HCl |
包装规格 | 1MG |
CAS编号 | 899431-18-6 |
别名 | A-438079 HCl |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C13H9Cl2N5 HCl
分子量:342.61
溶剂:DMSO (>25 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):P2X7 antagonist
Function / Pharmacology:A-438079 (899431-18-6) is a competitive P2X7 receptor antagonist (pIC50 = 6.9).1 Displayed antinociceptive effects in a rat model of neuropathic pain.2? A-438079 prevented the LPS-induced release of IL-1? and attenuated LPS-induced (via intrathecal lumbar injection) mechanical hyperalgesia in rat hindpaws.3? It prevented mechanical hyperalgesia following peripheral nerve injury.4 A-438079 protected against cerebral ischemia/reperfusion injury in a rat model via reduction of the neuroinflammatory response.5
分子式:C13H9Cl2N5 HCl
分子量:342.61
溶剂:DMSO (>25 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):P2X7 antagonist
Function / Pharmacology:A-438079 (899431-18-6) is a competitive P2X7 receptor antagonist (pIC50 = 6.9).1 Displayed antinociceptive effects in a rat model of neuropathic pain.2? A-438079 prevented the LPS-induced release of IL-1? and attenuated LPS-induced (via intrathecal lumbar injection) mechanical hyperalgesia in rat hindpaws.3? It prevented mechanical hyperalgesia following peripheral nerve injury.4 A-438079 protected against cerebral ischemia/reperfusion injury in a rat model via reduction of the neuroinflammatory response.5