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SIC5-6
- 英文名称：SIC5-6
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11099
- cas：2410846-16-9
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11099 |
| 用途 | 科研检测 |
| 英文名称 | SIC5-6 |
| 包装规格 | 1MG |
| CAS编号 | 2410846-16-9 |
| 别名 | SIC5-6 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:97% by HPLC;NMR (Conforms)
分子式:C27H24IN3O2S
分子量:581.47
溶剂:DMSO (>50 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Separase inhibitor
Function / Pharmacology:Separase is a cysteine protease that triggers chromosome segregation during mitosis and is highly overexpressed in many cancers. SIC5-6 is an inhibitor of separase with no inhibition of the related protease caspase-1 in vitro. HeLa cells with dysregulated separase activity showed severe chromosome segregation defects on treatment with 30 μM SIC5-6 indicating a potential attractive new chemotherapeutic target.
分子式:C27H24IN3O2S
分子量:581.47
溶剂:DMSO (>50 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Separase inhibitor
Function / Pharmacology:Separase is a cysteine protease that triggers chromosome segregation during mitosis and is highly overexpressed in many cancers. SIC5-6 is an inhibitor of separase with no inhibition of the related protease caspase-1 in vitro. HeLa cells with dysregulated separase activity showed severe chromosome segregation defects on treatment with 30 μM SIC5-6 indicating a potential attractive new chemotherapeutic target.
