|
VY-3-135
- 英文名称：VY-3-135
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11106
- cas：1824637-41-3
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-16
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11106 |
| 用途 | 科研检测 |
| 英文名称 | VY-3-135 |
| 包装规格 | 1MG |
| CAS编号 | 1824637-41-3 |
| 别名 | VY-3-135 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C26H27N3O3
分子量:429.52
溶剂:DMSO (>25 mg/ml)
性状:Off-white to pale yellow solid
存储:-20°C
Activity (short version):Acetyl-CoA synthetase 2 inhibitor
Function / Pharmacology:Potent (IC50 = 44 nM) and selective inhibitor of acetyl-CoA synthetase 2 (ACSS2), an enzyme that is upregulated in nutrient-stressed cancer cells.1 It completely blocked fatty acid synthesis from acetate in SKBR3 breast cancer cells. VY-3-135 caused growth inhibition of mouse and human triple negative breast cancer cells that expressed high levels of ACSS2 but not those that expressed low levels. It displayed no effects on gene regulation.
分子式:C26H27N3O3
分子量:429.52
溶剂:DMSO (>25 mg/ml)
性状:Off-white to pale yellow solid
存储:-20°C
Activity (short version):Acetyl-CoA synthetase 2 inhibitor
Function / Pharmacology:Potent (IC50 = 44 nM) and selective inhibitor of acetyl-CoA synthetase 2 (ACSS2), an enzyme that is upregulated in nutrient-stressed cancer cells.1 It completely blocked fatty acid synthesis from acetate in SKBR3 breast cancer cells. VY-3-135 caused growth inhibition of mouse and human triple negative breast cancer cells that expressed high levels of ACSS2 but not those that expressed low levels. It displayed no effects on gene regulation.
