纯度:98% by TLC [ 5% methanol in methylene chloride; Rf = 0.50] HR Mass Spec. (Conforms)
分子式:C29H35N2O2ClP
分子量:510.03
溶剂:Water (40 mg/ml) DMSO (25 mg/ml) Ethanol (40 mg/ml)
性状:Pale orange solid
存储:-20°C
Activity (short version):Mitochondria targeted antioxidant
Function / Pharmacology:Mitochondria-targeted antioxidant. Partially prevents mitochondrial permeability transition pore opening, necrosis and mitochondrial apoptosis after ATP depletion recovery.1 Resolves mitochondrial oxidative stress and rescues coronary collateral growth in Zucker obese fatty rats.2 Protects mitochondrial membrane potential and attenuates reperfusion-induced ROS production in a mouse ventricular myocyte model.3 Abrogates the induction of senescence in a human vascular smooth muscle cell model.4