|
N6022
- 英文名称：N6022
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11111
- cas：1208315-24-5
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11111 |
| 用途 | 科研检测 |
| 英文名称 | N6022 |
| 包装规格 | 1MG |
| CAS编号 | 1208315-24-5 |
| 别名 | N6022 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C24H22N4O3
分子量:414.46
溶剂:DMSO >25 mg/ml
性状:White solid
存储:-20°C
Activity (short version):S-Nitrosogluthione reductase inhibitor
Function / Pharmacology:N6022 is a potent and reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) – IC50 = 20 nM1, 8 nM2. It demonstrated significant efficacy in a mouse models of ovalbumin-induced asthma, chronic obstructive pulmonary disease, and irritable bowel syndrome. N6022 was able to attenuate experimental autoimmune encephalomyelitis (an animal model of multiple sclerosis) via selective inhibition of pro-inflammatory CD4+ cells (TH1/TH17) while upregulating anti-inflammatory subsets of CD4+ cells (TH2/Treg) without causing lymphopenia.3
分子式:C24H22N4O3
分子量:414.46
溶剂:DMSO >25 mg/ml
性状:White solid
存储:-20°C
Activity (short version):S-Nitrosogluthione reductase inhibitor
Function / Pharmacology:N6022 is a potent and reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) – IC50 = 20 nM1, 8 nM2. It demonstrated significant efficacy in a mouse models of ovalbumin-induced asthma, chronic obstructive pulmonary disease, and irritable bowel syndrome. N6022 was able to attenuate experimental autoimmune encephalomyelitis (an animal model of multiple sclerosis) via selective inhibition of pro-inflammatory CD4+ cells (TH1/TH17) while upregulating anti-inflammatory subsets of CD4+ cells (TH2/Treg) without causing lymphopenia.3
