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AZD7648
- 英文名称：AZD7648
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11113
- cas：2230820-11-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-16
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11113 |
| 用途 | 科研检测 |
| 英文名称 | AZD7648 |
| 包装规格 | 1MG |
| CAS编号 | 2230820-11-6 |
| 别名 | AZD7648 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C18H20N8O2
分子量:380.41
溶剂:DMSO (5 mg/ml with warming)
性状:White solid
存储:-20°C
Activity (short version):DNA-PK inhibitor/CRISPR enhancer
Function / Pharmacology:AZD7648 is a very potent and selective (against 397 kinases) DNA-PK inhibitor (pIC50 = 9.2; cellular pIC50 = 7.0).1 It is a sensitizer of radiation- and doxorubicin-induced DNA damage and sustained tumor regression in xenograft and patient-derived xenograft models.2 AZD7648 significantly enhances precise CRISPR/Cas9 gene editing alone3,4,5 or in combined treatment with a DNA polymerase theta inhibitor (2iHDR cocktail)5.
分子式:C18H20N8O2
分子量:380.41
溶剂:DMSO (5 mg/ml with warming)
性状:White solid
存储:-20°C
Activity (short version):DNA-PK inhibitor/CRISPR enhancer
Function / Pharmacology:AZD7648 is a very potent and selective (against 397 kinases) DNA-PK inhibitor (pIC50 = 9.2; cellular pIC50 = 7.0).1 It is a sensitizer of radiation- and doxorubicin-induced DNA damage and sustained tumor regression in xenograft and patient-derived xenograft models.2 AZD7648 significantly enhances precise CRISPR/Cas9 gene editing alone3,4,5 or in combined treatment with a DNA polymerase theta inhibitor (2iHDR cocktail)5.
