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H-151
- 英文名称:H-151
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11128
- cas:941987-60-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11128 |
用途 | 科研检测 |
英文名称 | H-151 |
包装规格 | 1MG |
CAS编号 | 941987-60-6 |
别名 | H-151 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98%,;NMR (Conforms)
分子式:C17H17N3O
分子量:279.34
溶剂:DMSO (25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):STING antagonist
Function / Pharmacology:H-151 is an inhibitor of the signaling molecule STING in mouse and human cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. It reduced systemic cytokine response in mice treated with the STING agonist 10-carboxymethyl-9-acridanone and showed efficacy in Trex-/- mice.
分子式:C17H17N3O
分子量:279.34
溶剂:DMSO (25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):STING antagonist
Function / Pharmacology:H-151 is an inhibitor of the signaling molecule STING in mouse and human cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. It reduced systemic cytokine response in mice treated with the STING agonist 10-carboxymethyl-9-acridanone and showed efficacy in Trex-/- mice.