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NVS-STG2
- 英文名称:NVS-STG2
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11130
- cas:3030588-01-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11130 |
用途 | 科研检测 |
英文名称 | NVS-STG2 |
包装规格 | 1MG |
CAS编号 | 3030588-01-0 |
别名 | NVS-STG2 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C25H33NO5
分子量:427.54
溶剂:DMSO (40 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Molecular glue STING agonist
Function / Pharmacology:NVS-STG2 is a STING agonist that activates human STING by binding in a pocket between the transmembrane domains of neighboring STING dimers in a molecular glue-like manner (AC50 = 5.2 μM). Inactive with mouse STING. NVS-STG2 slowed tumor growth significantly in MC38 tumors inoculated into hSTING knock-in mice.
分子式:C25H33NO5
分子量:427.54
溶剂:DMSO (40 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Molecular glue STING agonist
Function / Pharmacology:NVS-STG2 is a STING agonist that activates human STING by binding in a pocket between the transmembrane domains of neighboring STING dimers in a molecular glue-like manner (AC50 = 5.2 μM). Inactive with mouse STING. NVS-STG2 slowed tumor growth significantly in MC38 tumors inoculated into hSTING knock-in mice.