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Gilteritinib
- 英文名称:Gilteritinib
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11139
- cas:1254053-43-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11139 |
用途 | 科研检测 |
英文名称 | Gilteritinib |
包装规格 | 1MG |
CAS编号 | 1254053-43-4 |
别名 | Gilteritinib |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C29H44N8O3
分子量:552.72
溶剂:DMSO (25 mg/ml)
性状:Off-white to pale pink solid
存储:-20°C
Activity (short version):FLT3 inhibitor
Function / Pharmacology:Potent inhibitor of FLT3 (IC50 = 5 nM, wild-type FLT3) with more potent activity against all FLT3 mutants.1 It also potently inhibits Axl (IC50 = 41 nM). Clinically useful in the treatment of acute myeloid leukemia. Gilteritinib has also been shown to inhibit glutamine uptake and utilization via downregulation of glutamine transporters.2
分子式:C29H44N8O3
分子量:552.72
溶剂:DMSO (25 mg/ml)
性状:Off-white to pale pink solid
存储:-20°C
Activity (short version):FLT3 inhibitor
Function / Pharmacology:Potent inhibitor of FLT3 (IC50 = 5 nM, wild-type FLT3) with more potent activity against all FLT3 mutants.1 It also potently inhibits Axl (IC50 = 41 nM). Clinically useful in the treatment of acute myeloid leukemia. Gilteritinib has also been shown to inhibit glutamine uptake and utilization via downregulation of glutamine transporters.2