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PITSTOP2
- 英文名称：PITSTOP2
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11147
- cas：1332879-52-3
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-16
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11147 |
| 用途 | 科研检测 |
| 英文名称 | PITSTOP2 |
| 包装规格 | 1MG |
| CAS编号 | 1332879-52-3 |
| 别名 | PITSTOP2 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by TLC;NMR (Conforms)
分子式:C20H13BrN2O3S2
分子量:473.36
溶剂:DMSO (>30 mg/ml)
性状:Pink solid
存储:-20°C
Activity (short version):Clathrin-mediated endocystosis inhibitor
Function / Pharmacology:PITSTOP2 inhibits clathrin-mediated endocytosis via blockade of endocytic ligand association with the clathrin terminal domain leading to clathrin coat assembly inhibition.1 It was able to cause a collapse of the nucleocytoplasmic permeability barrier and a reduction of Importin-? binding.2 PITSTOP2 reduced viability in HeLa cells by trapping dividing cells in metaphase through loss of mitotic spindle integrity.3
分子式:C20H13BrN2O3S2
分子量:473.36
溶剂:DMSO (>30 mg/ml)
性状:Pink solid
存储:-20°C
Activity (short version):Clathrin-mediated endocystosis inhibitor
Function / Pharmacology:PITSTOP2 inhibits clathrin-mediated endocytosis via blockade of endocytic ligand association with the clathrin terminal domain leading to clathrin coat assembly inhibition.1 It was able to cause a collapse of the nucleocytoplasmic permeability barrier and a reduction of Importin-? binding.2 PITSTOP2 reduced viability in HeLa cells by trapping dividing cells in metaphase through loss of mitotic spindle integrity.3
