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NE-100
- 英文名称：NE-100
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11149
- cas：149409-57-4
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11149 |
| 用途 | 科研检测 |
| 英文名称 | NE-100 |
| 包装规格 | 1MG |
| CAS编号 | 149409-57-4 |
| 别名 | NE-100 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C23H33NO2·HCl
分子量:391.97
溶剂:DMSO (>25 mg/ml) Water (10 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Sigma-1 antagonist
Function / Pharmacology:NE-100 is potent inhibitor of the sigma receptor (?) with selectivity for sigma-1 (IC50 = 1.5 nM) over sigma-2 (IC50 = 85 nM).1,2 NE-100 suppressed ischemia-induced neuronal cell death in mice via upregulation of GPR78 through the ATF6 pathway resulting in suppression of ER stress-induced cell death in a sigma 1 independent manner.3
分子式:C23H33NO2·HCl
分子量:391.97
溶剂:DMSO (>25 mg/ml) Water (10 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Sigma-1 antagonist
Function / Pharmacology:NE-100 is potent inhibitor of the sigma receptor (?) with selectivity for sigma-1 (IC50 = 1.5 nM) over sigma-2 (IC50 = 85 nM).1,2 NE-100 suppressed ischemia-induced neuronal cell death in mice via upregulation of GPR78 through the ATF6 pathway resulting in suppression of ER stress-induced cell death in a sigma 1 independent manner.3
