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BD1063 dihydrochloride
- 英文名称：BD1063 dihydrochloride
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11155
- cas：206996-13-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11155 |
| 用途 | 科研检测 |
| 英文名称 | BD1063 dihydrochloride |
| 包装规格 | 1MG |
| CAS编号 | 206996-13-6 |
| 别名 | BD1063 dihydrochloride |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C13H18Cl2N2·2HCl
分子量:346.13
溶剂:Water (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Sigma-1 antagonist
Function / Pharmacology:BD1063 is potent and selective sigma-1 antagonist (IC50’s: sigma1 = 9nM, sigma2 = 449nM).1 BD1063 abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a sigma1 dependent manner.2 BD1063 potentiated μ-opioid antinociception in mice in a sigma-dependent manner.3 BD-1063 has been used in animal models to successfully treat compulsive eating4 and excessive ethanol drinking5.
分子式:C13H18Cl2N2·2HCl
分子量:346.13
溶剂:Water (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Sigma-1 antagonist
Function / Pharmacology:BD1063 is potent and selective sigma-1 antagonist (IC50’s: sigma1 = 9nM, sigma2 = 449nM).1 BD1063 abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a sigma1 dependent manner.2 BD1063 potentiated μ-opioid antinociception in mice in a sigma-dependent manner.3 BD-1063 has been used in animal models to successfully treat compulsive eating4 and excessive ethanol drinking5.
