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Mirabegron
- 英文名称:Mirabegron
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11157
- cas:223673-61-8
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11157 |
用途 | 科研检测 |
英文名称 | Mirabegron |
包装规格 | 1MG |
CAS编号 | 223673-61-8 |
别名 | Mirabegron |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C21H24N4O2S
分子量:396.51
溶剂:DMSO (40 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):beta-3 Adrenergic agonist
Function / Pharmacology:Mirabegron is a potent (EC50 = 22.4 nM CHO cells expressing human ?3-ARs) beta-3 adrenergic receptor (?3-AR) agonist with high selectivity over the beta-1 and beta-2 receptors.1 Clinically useful for the treatment of overactive bladder syndrome. Chronic treatment of human subjects with mirabegron increased brown adipose tissue (BAT) metabolic activity, increased HDL and bile acid levels, and produced substantial improvements in glucose and insulin metabolism.2 Mirabegron inhibited tumor growth in various tumor models including pancreatic ductal adenocarcinoma and hepatocellular carcinoma via altering global metabolism in an uncoupling protein 1 (UCP1; a key protein for non-shivering thermogenesis) dependent manner.3
分子式:C21H24N4O2S
分子量:396.51
溶剂:DMSO (40 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):beta-3 Adrenergic agonist
Function / Pharmacology:Mirabegron is a potent (EC50 = 22.4 nM CHO cells expressing human ?3-ARs) beta-3 adrenergic receptor (?3-AR) agonist with high selectivity over the beta-1 and beta-2 receptors.1 Clinically useful for the treatment of overactive bladder syndrome. Chronic treatment of human subjects with mirabegron increased brown adipose tissue (BAT) metabolic activity, increased HDL and bile acid levels, and produced substantial improvements in glucose and insulin metabolism.2 Mirabegron inhibited tumor growth in various tumor models including pancreatic ductal adenocarcinoma and hepatocellular carcinoma via altering global metabolism in an uncoupling protein 1 (UCP1; a key protein for non-shivering thermogenesis) dependent manner.3