纯度:98% by HPLC, NMR (Confirms)
分子式:C26H27F4N3O7
分子量:569.51
溶剂:DMSO (20 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):pan-Caspase inhibitor
Function / Pharmacology:Emricasan is a liver-targeted antiapoptotic pan-caspase inhibitor.1,2 It has been investigated as a hepatoprotective agent in the treatment of liver ischemia3 and NASH/NAFLD liver injury4,5. Emricasan protected SNB-19 cells against cell death induced by Zika virus strains MR766, FSS13025, and PRVABC59.6 Emricasan improves the viability of hPSCs and their differentiated progeny when used in a small molecule cocktail (CEPT) containing chroman 1, polyamines and trans-ISRIB.7