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ERGi-USU
- 英文名称：ERGi-USU
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11172
- cas：1147-56-4
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11172 |
| 用途 | 科研检测 |
| 英文名称 | ERGi-USU |
| 包装规格 | 1MG |
| CAS编号 | 1147-56-4 |
| 别名 | ERGi-USU |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC NMR (Confirms)
分子式:C13H9N3OS
分子量:255.30
溶剂:DMSO (>10 mg/ml)
性状:Red or Orange solid
存储:-20°C
Activity (short version):ERG inhibitor
Function / Pharmacology:ERGi-USU selectively inhibits the growth of ERG-positive VCaP prostate cancer cells, COLO320 colon cancer cells, KG-1 and MOLT-4 leukemia cells with minimal effect on ERG-negative cells or normal prostate or endothelial cells (IC50 = 169 nM for cell growth and 315 nM for ERG protein in VCaP cells). It selectively inhibits the kinase RIOK2 (Kd = 200 nM) causing disruption of ribosomal biogenesis and ribosomal stress.
分子式:C13H9N3OS
分子量:255.30
溶剂:DMSO (>10 mg/ml)
性状:Red or Orange solid
存储:-20°C
Activity (short version):ERG inhibitor
Function / Pharmacology:ERGi-USU selectively inhibits the growth of ERG-positive VCaP prostate cancer cells, COLO320 colon cancer cells, KG-1 and MOLT-4 leukemia cells with minimal effect on ERG-negative cells or normal prostate or endothelial cells (IC50 = 169 nM for cell growth and 315 nM for ERG protein in VCaP cells). It selectively inhibits the kinase RIOK2 (Kd = 200 nM) causing disruption of ribosomal biogenesis and ribosomal stress.
