![]() |
XMU-MP-1
- 英文名称:XMU-MP-1
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11174
- cas:2061980-01-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11174 |
用途 | 科研检测 |
英文名称 | XMU-MP-1 |
包装规格 | 1MG |
CAS编号 | 2061980-01-4 |
别名 | XMU-MP-1 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC,;NMR (Conforms)
分子式:C17H16N6O3S2
分子量:416.47
溶剂:DMSO (15 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Potent and selective MST1/2 kinase inhibitor
Function / Pharmacology:XMU-MP-1 is a potent, reversible, and selective inhibitor of the HIPPO pathway kinases MST1 and MST2 (IC50s = 71 nM and 38 nM respectively).1 It promoted liver repair/regeneration in mice and attenuated acetaminophen-induced liver injury. In a subarachnoid hemorrhage mouse model, XMU-MP-1 alleviated neurological deficits, brain edema, neuroinflammation, and white matter injury.2 XMU-MP-1 was also cardioprotective in mice with transverse aortic constriction3 and against ischemia/reperfusion injury4.
分子式:C17H16N6O3S2
分子量:416.47
溶剂:DMSO (15 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Potent and selective MST1/2 kinase inhibitor
Function / Pharmacology:XMU-MP-1 is a potent, reversible, and selective inhibitor of the HIPPO pathway kinases MST1 and MST2 (IC50s = 71 nM and 38 nM respectively).1 It promoted liver repair/regeneration in mice and attenuated acetaminophen-induced liver injury. In a subarachnoid hemorrhage mouse model, XMU-MP-1 alleviated neurological deficits, brain edema, neuroinflammation, and white matter injury.2 XMU-MP-1 was also cardioprotective in mice with transverse aortic constriction3 and against ischemia/reperfusion injury4.