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SLB1122168
  • 英文名称:SLB1122168
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B11196
  • cas:2999629-17-1
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-12
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B11196
用途 科研检测
英文名称 SLB1122168
包装规格 1MG
CAS编号 2999629-17-1
别名 SLB1122168
纯度 98+%
分子式
是否进口
纯度:>98% by HPLC;NMR (Conforms)
分子式:C22H35N3O·HCl
分子量:394
溶剂:DMSO (40 mg/ml); Water (10 mg/ml with warming)
性状:Off-white solid
存储:-20°C
Activity (short version):Spns2 inhibitor
Function / Pharmacology:SLB1122168 is a potent (IC50 = 94 nM) second generation sphingosine-1-phosphate transporter Spinster Homolog 2 (Spns2) inhibitor. In vivo, it significantly reduced circulating lymphocyte counts but did not reduce plasma sphigosine-1-phosphate levels as with the first generation inhibitor SLF1081851 (Focus Cat# 10-4395). Spns2 inhibitors represent potential alternative immunomodulatory agents to S1P receptor agonists as they are able in induce lymphopenia without drastic changes to systemic S1P levels or stimulating the S1P1-5 signaling pathway.
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