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XL413·HCl
- 英文名称：XL413·HCl
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11203
- cas：2062200-97-7
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11203 |
| 用途 | 科研检测 |
| 英文名称 | XL413·HCl |
| 包装规格 | 1MG |
| CAS编号 | 2062200-97-7 |
| 别名 | XL413·HCl |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C14H12ClN3O2·HCl
分子量:326.18
溶剂:DMSO (2 mg/ml with warming); water (7 mg/ml with warming)
性状:White solid
存储:-20°C
Activity (short version):Cdc7 inhibitor/CRISPR enhancer
Function / Pharmacology:XL413 is a potent (IC50 = 4.8 nM) ATP-competitive inhibitor of the important DNA replication initiation kinase Cdc7 (DDK).1 It increases the efficiency of homology directed DNA repair in CRISPR-Cas9 gene editing.2 XL413 acted synergistically with other chemotherapy agents in various cancer models.3-5
分子式:C14H12ClN3O2·HCl
分子量:326.18
溶剂:DMSO (2 mg/ml with warming); water (7 mg/ml with warming)
性状:White solid
存储:-20°C
Activity (short version):Cdc7 inhibitor/CRISPR enhancer
Function / Pharmacology:XL413 is a potent (IC50 = 4.8 nM) ATP-competitive inhibitor of the important DNA replication initiation kinase Cdc7 (DDK).1 It increases the efficiency of homology directed DNA repair in CRISPR-Cas9 gene editing.2 XL413 acted synergistically with other chemotherapy agents in various cancer models.3-5
