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Sulfopin
- 英文名称:Sulfopin
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11213
- cas:2451481-08-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11213 |
用途 | 科研检测 |
英文名称 | Sulfopin |
包装规格 | 1MG |
CAS编号 | 2451481-08-4 |
别名 | Sulfopin |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C11H20ClNO3S
分子量:281.8
溶剂:DMSO (25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Potent and selective covalent inhibitor of peptidyl-prolyl isomerase NIMA interacting-1 (Pin1)
Function / Pharmacology:Potent and selective covalent inhibitor of peptidyl-prolyl isomerase NIMA interacting-1 (Pin1) (Ki = 17 nM).1 Although it displayed little to no cytotoxicity against a panel of 300 cancer cell lines, it had a significant impact on cancer cell growth after prolonged treatment. It suppressed MYCN-driven neuroblastoma initiation and the growth and survival of primary neuroblastoma tumor cell transplants in zebrafish.
分子式:C11H20ClNO3S
分子量:281.8
溶剂:DMSO (25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Potent and selective covalent inhibitor of peptidyl-prolyl isomerase NIMA interacting-1 (Pin1)
Function / Pharmacology:Potent and selective covalent inhibitor of peptidyl-prolyl isomerase NIMA interacting-1 (Pin1) (Ki = 17 nM).1 Although it displayed little to no cytotoxicity against a panel of 300 cancer cell lines, it had a significant impact on cancer cell growth after prolonged treatment. It suppressed MYCN-driven neuroblastoma initiation and the growth and survival of primary neuroblastoma tumor cell transplants in zebrafish.