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Ruxolitinib
- 英文名称：Ruxolitinib
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11243
- cas：941678-49-5
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11243 |
| 用途 | 科研检测 |
| 英文名称 | Ruxolitinib |
| 包装规格 | 1MG |
| CAS编号 | 941678-49-5 |
| 别名 | Ruxolitinib |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:99% by HPLC,;NMR (Conforms)
分子式:C17H18N6
分子量:306.37
溶剂:DMSO (28 mg/ml) Ethanol (15 mg/ml with warming)
性状:White solid
存储:-20°C
Activity (short version):JAK inhibitor
Function / Pharmacology:Potent and selective JAK1&2 inhibitor, IC50s=2.7, 4.5 and 322 nM forJAK1, JAK2 and JAK3 respectively.1 Blocks IL-6 signaling (IC50=281 nM) and proliferation of JAK2V617F+ Ba/F3 cells (IC50=127 nM).2 Inhibits the proinflammatory secretome of senescent cells.3 The JAK1 S646P mutant is highly sensitive to ruxolitinib.4 Clinically useful cancer chemotherapeutic.
分子式:C17H18N6
分子量:306.37
溶剂:DMSO (28 mg/ml) Ethanol (15 mg/ml with warming)
性状:White solid
存储:-20°C
Activity (short version):JAK inhibitor
Function / Pharmacology:Potent and selective JAK1&2 inhibitor, IC50s=2.7, 4.5 and 322 nM forJAK1, JAK2 and JAK3 respectively.1 Blocks IL-6 signaling (IC50=281 nM) and proliferation of JAK2V617F+ Ba/F3 cells (IC50=127 nM).2 Inhibits the proinflammatory secretome of senescent cells.3 The JAK1 S646P mutant is highly sensitive to ruxolitinib.4 Clinically useful cancer chemotherapeutic.
