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Zoledronic acid
  • 英文名称:Zoledronic acid
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B11244
  • cas:118072-93-8
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-23
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B11244
用途 科研检测
英文名称 Zoledronic acid
包装规格 1MG
CAS编号 118072-93-8
别名 Zoledronic acid
纯度 98+%
分子式
是否进口
纯度:98% by HPLC
分子式:C5H10N2O7P2
分子量:272.09
溶剂:Water (2 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Antiproliferative and apopototic effects
Function / Pharmacology:Potent inhibitor of bone resorption (IC50 = 2 nM in mouse calvarial cultures).1 The mechanism of its action is thought to be via inhibition of osteoclastic activity, induction of osteoclast apoptosis and blockage of osteoclastic resorption of mineralized bone and cartilage through its binding to bone. Clinically useful drug for treatment of osteoporosis2, hypercalcemia of malignancy(HCM), multiple myeloma and bone metastases from solid tumors3. It has also been investigated as an antitumor agent and showing efficacy as an adjuvant therapy in several cancers.4,5
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