菜单 Close 公司首页 公司介绍 公司动态 证书荣誉 联系方式 在线留言
您当前的位置: 网站首页 > 产品展厅 >药物类 >Harmine HCl
Harmine HCl
  • 英文名称:Harmine HCl
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B11252
  • cas:343-27-1
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-23
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B11252
用途 科研检测
英文名称 Harmine HCl
包装规格 1MG
CAS编号 343-27-1
别名 Harmine HCl
纯度 98+%
分子式
是否进口
纯度:>98% (TLC: 10% Methanol/methylene chloride + 0.5% NH4OH; Rf = 0.50)
分子式:C13H12N2O·HCl
分子量:248.71
溶剂:Water (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):MAO-A and DYRK inhibitor
Function / Pharmacology:Selective competitive and reversible inhibitor of MAO-A (IC50 = 8 μM).1 Harmine is a potent and specific inhibitor of both the kinase activity and autophosphorylation of tyrosine during translation DYRK1A (IC50’s: DYRKA1A = 33 nM; DYRKA1B = 166 nM; DYRK2 = 1.9 μM; DYRK4 = 80 μM).2,3 Inhibits self-renewal and promotes differentiation of glioblastoma stem-like cells(GSLC’s) possibly via inhibition of Akt phosphorylation.4 Harmine has also been shown to possess antimicrobial, antifungal, antiplasmodial, antitumor, antioxidant, antimutagenic and antigenotoxic properties.5 Inhibits osteoclast differentiation and bone resorption via downregulation of c-Fos and NFATc1 induced by RANKL.6
联系方式
手机:15317051735
Q Q:
二维码扫描访问