纯度:98% by TLC;NMR (Conforms)
分子式:C16H28O3
分子量:268.39
溶剂:DMSO or Ethanol
性状:Colorless oil
存储:-20°C
Activity (short version):RXR agonist
Function / Pharmacology:Methoprene acid (53092-52-7) is an analog of insect juvenile hormone which acts as an insect growth regulator. Binds directly and selectively to the retinoid X receptor (RXR) acting as a transcriptional activator in both insect and mammalian cells with no activity at RAR.1 Negatively regulates thrombosis and hemostasis.2 Induces neurosteroid biosynthesis in human glial GI-1 cells.3 Increases the expression of the brown-fat-uncoupling-protein-1 gene (ucp-1).4