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RepSox
- 英文名称:RepSox
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11273
- cas:446859-33-2
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11273 |
用途 | 科研检测 |
英文名称 | RepSox |
包装规格 | 1MG |
CAS编号 | 446859-33-2 |
别名 | RepSox |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:99% by HPLC,;NMR (Conforms)
分子式:C17H13N5
分子量:287.32
溶剂:DMSO (>25 mg/ml) Ethanol (10 mg/ml)
性状:Pale yellow solid
存储:-20°C
Activity (short version):TGFβR-1 / ALK5 inhibitor
Function / Pharmacology:RepSox is a potent (IC50 ALK5 auto-P= 4 nM; IC50 TGF-b cellular assay = 23 nM) inhibitor of the TGF-β type I receptor (ALK5).1 RepSox can replace Sox2 in reprogramming adult cells into pluripotent stem cells via induction of Nanog transcription.2 It was able to convert astrocytes into neuronal cells as part of a small molecule cocktail (along with valproic acid and CHIR99021).3,4
分子式:C17H13N5
分子量:287.32
溶剂:DMSO (>25 mg/ml) Ethanol (10 mg/ml)
性状:Pale yellow solid
存储:-20°C
Activity (short version):TGFβR-1 / ALK5 inhibitor
Function / Pharmacology:RepSox is a potent (IC50 ALK5 auto-P= 4 nM; IC50 TGF-b cellular assay = 23 nM) inhibitor of the TGF-β type I receptor (ALK5).1 RepSox can replace Sox2 in reprogramming adult cells into pluripotent stem cells via induction of Nanog transcription.2 It was able to convert astrocytes into neuronal cells as part of a small molecule cocktail (along with valproic acid and CHIR99021).3,4