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NHI-2
- 英文名称：NHI-2
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11279
- cas：1269802-97-2
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11279 |
| 用途 | 科研检测 |
| 英文名称 | NHI-2 |
| 包装规格 | 1MG |
| CAS编号 | 1269802-97-2 |
| 别名 | NHI-2 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC, NMR (Confirms)
分子式:C17H12F3NO3
分子量:335.28
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):LDHA inhibitor
Function / Pharmacology:NHI-2 is a selective inhibitor of Lactate Dehydrogenase A (LDHA) – IC50 in vitro = 14.7 μM (NADH), 10.5 μM (Pyruvate).1 NHI-2 has also shown cellular growth inhibitory effects against pancreatic cancer cells (PANC-1 cells IC50 = 22.2 μM normoxic and 4.0 μM hypoxic; LPC006 cells IC50 = 17.8 μM normoxic and 1.1 μM hypoxic) with increased efficacy in a cancer cells hypoxic environment.2 LDHA is a key enzyme involved in the Warburg effect and a cancer cells ability to survive in a hypoxic environment.
分子式:C17H12F3NO3
分子量:335.28
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):LDHA inhibitor
Function / Pharmacology:NHI-2 is a selective inhibitor of Lactate Dehydrogenase A (LDHA) – IC50 in vitro = 14.7 μM (NADH), 10.5 μM (Pyruvate).1 NHI-2 has also shown cellular growth inhibitory effects against pancreatic cancer cells (PANC-1 cells IC50 = 22.2 μM normoxic and 4.0 μM hypoxic; LPC006 cells IC50 = 17.8 μM normoxic and 1.1 μM hypoxic) with increased efficacy in a cancer cells hypoxic environment.2 LDHA is a key enzyme involved in the Warburg effect and a cancer cells ability to survive in a hypoxic environment.
