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Indoximod
- 英文名称:Indoximod
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11290
- cas:110117-83-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11290 |
用途 | 科研检测 |
英文名称 | Indoximod |
包装规格 | 1MG |
CAS编号 | 110117-83-4 |
别名 | Indoximod |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98%,;NMR (Conforms)
分子式:C12H14N2O2
分子量:218.25
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):IDO modulator / tryptophan mimetic
Function / Pharmacology:Indoximod is a modulator of indoleamine 2,3-dioxygenase (IDO) activity.1 IDO can be used by tumors to avoid elimination by the host immune response2,3, thus inhibition of IDO is an interesting cancer therapeutic option. Indoximod is not a direct inhibitor of IDO, but instead targets the IDO gene leading to downstream effects.3 IDO-mediated catabolism of tryptophan inhibits the immunoregulatory kinases mTOR and PKC5. This is relieved by Indoximod acting as a potent tryptophan mimetic restoring mTOR and PKC signaling.4
分子式:C12H14N2O2
分子量:218.25
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):IDO modulator / tryptophan mimetic
Function / Pharmacology:Indoximod is a modulator of indoleamine 2,3-dioxygenase (IDO) activity.1 IDO can be used by tumors to avoid elimination by the host immune response2,3, thus inhibition of IDO is an interesting cancer therapeutic option. Indoximod is not a direct inhibitor of IDO, but instead targets the IDO gene leading to downstream effects.3 IDO-mediated catabolism of tryptophan inhibits the immunoregulatory kinases mTOR and PKC5. This is relieved by Indoximod acting as a potent tryptophan mimetic restoring mTOR and PKC signaling.4