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Fumarate hydratase-IN-1
- 英文名称：Fumarate hydratase-IN-1
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11295
- cas：1644060-37-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11295 |
| 用途 | 科研检测 |
| 英文名称 | Fumarate hydratase-IN-1 |
| 包装规格 | 1MG |
| CAS编号 | 1644060-37-6 |
| 别名 | Fumarate hydratase-IN-1 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C27H30N2O4
分子量:446.55
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Fumarate hydratase inhibitor
Function / Pharmacology:Fumarate hydratase-IN-1 is a pro-drug inhibitor of fumarate hydratase, an important enzyme in the tricarboxylic acid (TCA) cycle. This cell permeable compound is converted to the active carboxylic acid by intracellular esterases (Ki = 4.5 μM for free acid). The ethyl ester displayed cell-growth inhibitory activity against several cancer lines under nutrient (glucose) deprived conditions with an average IC50 = 2.2 μM.
分子式:C27H30N2O4
分子量:446.55
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Fumarate hydratase inhibitor
Function / Pharmacology:Fumarate hydratase-IN-1 is a pro-drug inhibitor of fumarate hydratase, an important enzyme in the tricarboxylic acid (TCA) cycle. This cell permeable compound is converted to the active carboxylic acid by intracellular esterases (Ki = 4.5 μM for free acid). The ethyl ester displayed cell-growth inhibitory activity against several cancer lines under nutrient (glucose) deprived conditions with an average IC50 = 2.2 μM.
