纯度:98% by TLC,;NMR (Conforms)
分子式:C15H24N2O
分子量:248.36
溶剂:Water (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Induces RIP3-dependent necroptosis
Function / Pharmacology:Matrine is a natural product found in the plant Sophora flavescens. It has been found to possess myriad biological activities including a positive inotropic effect1,2, reduced glucose intolerance and hepatic steatosis in a mouse model via activation of HSP723, various anti-cancer effects4,5,6. Matrine has also recently been shown to induce RIP3-dependent necroptosis in cholangiocarcinoma cells.7