纯度:98% by HPLC,;NMR (Conforms)
分子式:C10H13N5O4
分子量:267.24
溶剂:DMSO (>40 mg/ml) Water (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Antiretroviral / Enhances CRISPR repair
Function / Pharmacology:Zidovudine was the first clinically useful antiretroviral medicine.1,2 Newer antiretroviral medications have replaced it in the clinic. It selectively inhibits reverse transcriptase acting via the triphosphate metabolite. Zidovudine has recently been found to enhance CRISPR-mediated homology-directed repair (HDR) efficiency.3