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NG-497
- 英文名称：NG-497
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11323
- cas：2598242-66-9
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11323 |
| 用途 | 科研检测 |
| 英文名称 | NG-497 |
| 包装规格 | 1MG |
| CAS编号 | 2598242-66-9 |
| 别名 | NG-497 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C18H21NO4
分子量:315.37
溶剂:DMSO (25 mg/ml with warming) Ethanol (20 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Human ATGL inhibitor
Function / Pharmacology:NG-497 is the first small molecule inhibitor (IC50 = 1 μM) of human and rhesus monkey adipose triglyceride lipase (ATGL). It is inactive against mouse, rat, goat, pig, dog, and marmoset ATGL orthologues. Of the eight enzymes expressed by humans in the patatin-like phospholipase domain-containing (PNPLA) protein family, NG-497 was selective for PNPLA 2 (ATGL). NG-497 was also inactive against HSL, CES2, LPL, and HL. Reversible and non-toxic.
分子式:C18H21NO4
分子量:315.37
溶剂:DMSO (25 mg/ml with warming) Ethanol (20 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Human ATGL inhibitor
Function / Pharmacology:NG-497 is the first small molecule inhibitor (IC50 = 1 μM) of human and rhesus monkey adipose triglyceride lipase (ATGL). It is inactive against mouse, rat, goat, pig, dog, and marmoset ATGL orthologues. Of the eight enzymes expressed by humans in the patatin-like phospholipase domain-containing (PNPLA) protein family, NG-497 was selective for PNPLA 2 (ATGL). NG-497 was also inactive against HSL, CES2, LPL, and HL. Reversible and non-toxic.
