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Azoramide
- 英文名称：Azoramide
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11326
- cas：932986-18-0
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11326 |
| 用途 | 科研检测 |
| 英文名称 | Azoramide |
| 包装规格 | 1MG |
| CAS编号 | 932986-18-0 |
| 别名 | Azoramide |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C15H17ClN2OS
分子量:308.83
溶剂:DMSO (>25 mg/ml) Ethanol (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):UPR modulator
Function / Pharmacology:Azoramide is a modulator of the unfolded protein response (UPR).1 It improves endoplasmic reticulum (ER) protein folding and activates ER chaperone capacity to protect cells against ER stress. It displayed potent anti-diabetic activity in two mouse models by improving insulin sensitivity and pancreatic β cell function. Azoramide increased SERCA expression leading to enhanced calcium retention in the ER indicating calcium homeostasis as a possible mechanism for its anti-diabetic acitivty.
分子式:C15H17ClN2OS
分子量:308.83
溶剂:DMSO (>25 mg/ml) Ethanol (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):UPR modulator
Function / Pharmacology:Azoramide is a modulator of the unfolded protein response (UPR).1 It improves endoplasmic reticulum (ER) protein folding and activates ER chaperone capacity to protect cells against ER stress. It displayed potent anti-diabetic activity in two mouse models by improving insulin sensitivity and pancreatic β cell function. Azoramide increased SERCA expression leading to enhanced calcium retention in the ER indicating calcium homeostasis as a possible mechanism for its anti-diabetic acitivty.
