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Clodronate 2Na
- 英文名称：Clodronate 2Na
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11328
- cas：88416-50-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11328 |
| 用途 | 科研检测 |
| 英文名称 | Clodronate 2Na |
| 包装规格 | 1MG |
| CAS编号 | 88416-50-6 |
| 别名 | Clodronate 2Na |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98%,;NMR (Conforms)
分子式:CH2Cl2O6P2·2Na·4H2O
分子量:360.92
溶剂:Water (>10 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Induces osteoclast apoptosis
Function / Pharmacology:Clodronate is a first generation non-nitrogenous bisphosphonate drug for the prevention and treatment of osteoporosis and skeletal fractures/hypercalcemia in patients with cancer. It strongly binds to hydroxyapatite and directly reduces osteoclast activity.1 Clodronate is metabolized in vitro to a cytotoxic ATP analog (AppCCl2p) which inhibits ADP/ATP translocase in the mitochondrial inner membrane leading to osteoclast apoptosis.2
分子式:CH2Cl2O6P2·2Na·4H2O
分子量:360.92
溶剂:Water (>10 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Induces osteoclast apoptosis
Function / Pharmacology:Clodronate is a first generation non-nitrogenous bisphosphonate drug for the prevention and treatment of osteoporosis and skeletal fractures/hypercalcemia in patients with cancer. It strongly binds to hydroxyapatite and directly reduces osteoclast activity.1 Clodronate is metabolized in vitro to a cytotoxic ATP analog (AppCCl2p) which inhibits ADP/ATP translocase in the mitochondrial inner membrane leading to osteoclast apoptosis.2
