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Nitazoxanide
  • 英文名称:Nitazoxanide
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B11329
  • cas:55981-09-4
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-12
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B11329
用途 科研检测
英文名称 Nitazoxanide
包装规格 1MG
CAS编号 55981-09-4
别名 Nitazoxanide
纯度 98+%
分子式
是否进口
纯度:99% by HPLC,;NMR (Conforms)
分子式:C12H9N3O5S
分子量:307.28
溶剂:DMSO (>50 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Antiviral and antiparasitic agent
Function / Pharmacology:Nitazoxanide is a clinically relevant antiparasitic agent.1It has since been repurposed as a broad-spectrum antiviral agent that is active against many RNA and DNA viruses including influenza, Hepatitis B and C, RSV, coronavirus, dengue and others.2 Its antiparasitic activity is believed to be due to inhibition of pyruvate:ferredoxin/flavodoxin oxidoreductases.3 Antiviral activity involves activation of protein kinase activated by double-stranded RNA (PKR) leading to phosphorylation of eukaryotic initiation factor 2 alpha (eIF2α).4 Nitazoxanide has also been found to inhibit Wnt signaling independent of adenomatous polyposis coli (APC) – it targets peptidyl arginine deiminase 2 (PAD2) resulting in increased citrullination of β-catenin.5
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