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PF-9366
- 英文名称:PF-9366
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11330
- cas:72882-78-1
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11330 |
用途 | 科研检测 |
英文名称 | PF-9366 |
包装规格 | 1MG |
CAS编号 | 72882-78-1 |
别名 | PF-9366 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C20H19ClN4
分子量:350.85
溶剂:DMSO (20 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):Methionine adenosyltransferase 2A inhibitor
Function / Pharmacology:PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50’s of 1.2 μM and 225 nM respectively.
分子式:C20H19ClN4
分子量:350.85
溶剂:DMSO (20 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):Methionine adenosyltransferase 2A inhibitor
Function / Pharmacology:PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50’s of 1.2 μM and 225 nM respectively.