|
PF-9366
- 英文名称：PF-9366
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11330
- cas：72882-78-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11330 |
| 用途 | 科研检测 |
| 英文名称 | PF-9366 |
| 包装规格 | 1MG |
| CAS编号 | 72882-78-1 |
| 别名 | PF-9366 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C20H19ClN4
分子量:350.85
溶剂:DMSO (20 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):Methionine adenosyltransferase 2A inhibitor
Function / Pharmacology:PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50’s of 1.2 μM and 225 nM respectively.
分子式:C20H19ClN4
分子量:350.85
溶剂:DMSO (20 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):Methionine adenosyltransferase 2A inhibitor
Function / Pharmacology:PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50’s of 1.2 μM and 225 nM respectively.
