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NS 1619
- 英文名称:NS 1619
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11333
- cas:153587-01-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11333 |
用途 | 科研检测 |
英文名称 | NS 1619 |
包装规格 | 1MG |
CAS编号 | 153587-01-0 |
别名 | NS 1619 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C15H8F6N2O2
分子量:362.23
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Selective KCa1.1 activator
Function / Pharmacology:NS 1619 is a selective activator of large conductance Ca(2+)-dependent potassium channels (BKCa or KCa1.1).1,2 It was able to increase blood-brain tumor barrier permeability in rat brain tumor models.3,4 NS 1619 inhibited proliferation and induced apoptosis in A2780 ovarian cancer cells.5 Displays cardioprotective effects in an ischemia-reperfusion model6 and neuroprotective effects in a traumatic brain injury model7.
分子式:C15H8F6N2O2
分子量:362.23
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Selective KCa1.1 activator
Function / Pharmacology:NS 1619 is a selective activator of large conductance Ca(2+)-dependent potassium channels (BKCa or KCa1.1).1,2 It was able to increase blood-brain tumor barrier permeability in rat brain tumor models.3,4 NS 1619 inhibited proliferation and induced apoptosis in A2780 ovarian cancer cells.5 Displays cardioprotective effects in an ischemia-reperfusion model6 and neuroprotective effects in a traumatic brain injury model7.