纯度:>98% by TLC;NMR (Conforms)
分子式:C21H26ClNO·C4H4O4
分子量:459.96
溶剂:DMSO (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Histamine H1 receptor antagonist
Function / Pharmacology:Histamine H1 antagonist with anti-muscarinic effects at the M1 receptor. Enhances remyelination in a mouse model of demyelination.1 Displays protective role against neuroinflammation and demyelination via anti-inflammatory and anti-pyroptotic actions.2 Clemastine promoted oligodendrocyte differentiation in a rat model of spinal cord injury via muscarinic receptor mediated activation of ERK1/2 signaling.3