菜单 Close 公司首页 公司介绍 公司动态 证书荣誉 联系方式 在线留言
您当前的位置: 网站首页 > 产品展厅 >药物类 >Nitisinone
Nitisinone
  • 英文名称:Nitisinone
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B11336
  • cas:104206-65-7
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-23
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B11336
用途 科研检测
英文名称 Nitisinone
包装规格 1MG
CAS编号 104206-65-7
别名 Nitisinone
纯度 98+%
分子式
是否进口
纯度:>98% by TLC (NMR Conforms)
分子式:C14H10F3NO5
分子量:329.23
溶剂:DMSO (>10 mg/ml) Ethanol (10 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):Tyrosine metabolism inhibitor
Function / Pharmacology:Inhibitor of 4-Hydroxyphenylpyruvate dioxygenase (HPPD; IC50 = 40 nM1 and 173 nM2) and is in clinical use for the treatment of hereditary tyrosinemia type 13. CD13+ cancer stem cells (CSCs) are dependent on aerobic metabolism of tyrosine - Nitisinone inhibition of tyrosine metabolism results in lowered availability of acetyl-CoA and fumarate for use in the citric acid cycle causing these CSCs to enter cell cycle, decreasing self-renewal, and making them more susceptible to chemotherapy.4 Nitisinone is a potential treatment option for cancers that rely on tyrosine metabolism.
联系方式
手机:15317051735
Q Q:
二维码扫描访问