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VU0810464
- 英文名称：VU0810464
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11348
- cas：2126040-21-7
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-11-26
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11348 |
| 用途 | 科研检测 |
| 英文名称 | VU0810464 |
| 包装规格 | 1MG |
| CAS编号 | 2126040-21-7 |
| 别名 | VU0810464 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by TLC (NMR Conforms)
分子式:C18H21ClFN3O
分子量:349.83
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Kir3 activator
Function / Pharmacology:VU0810464 is potent (Kir3.1/3.2; GIRK1/2 EC50 = 165 nM) activator of G protein-gated inwardly-rectifying potassium channels (Kir3; GIRK).1,2 Displays selectivity for Kir3.1/3.2 versus Kir3.1/3.4 as well as selectivity for neuronal versus cardiac Kir3 channels. VU0810464 reduced stress-induced hyperthermia but not anxiety-related behavior in mice.
分子式:C18H21ClFN3O
分子量:349.83
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Kir3 activator
Function / Pharmacology:VU0810464 is potent (Kir3.1/3.2; GIRK1/2 EC50 = 165 nM) activator of G protein-gated inwardly-rectifying potassium channels (Kir3; GIRK).1,2 Displays selectivity for Kir3.1/3.2 versus Kir3.1/3.4 as well as selectivity for neuronal versus cardiac Kir3 channels. VU0810464 reduced stress-induced hyperthermia but not anxiety-related behavior in mice.
