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PB28 dihydrochloride
- 英文名称：PB28 dihydrochloride
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11350
- cas：172907-03-8
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11350 |
| 用途 | 科研检测 |
| 英文名称 | PB28 dihydrochloride |
| 包装规格 | 1MG |
| CAS编号 | 172907-03-8 |
| 别名 | PB28 dihydrochloride |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:99% by HPLC;NMR (Conforms)
分子式:C24H38N2O·2HCl
分子量:443.50
溶剂:DMSO (>25 mg/ml) Water (5 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):High affinity sigma 2 ligand / Anti-SARS-COV2
Function / Pharmacology:PB28 is a very potent high affinity (Ki = 5.3 nM1, 0.34 nM2) sigma 2 agonist. Selective for sigma 2 over sigma1 (approx 30-40x).1,2 PB28 inhibited cell growth in MCF7 and MCF7 ADR breast cancer cells and displayed strong synergism with doxorubicin.3 PB28 potently inhibited Kv2.1 currents in a sigma-independent manner.4 PB28 was recently found to have potent (IC50 = 280 nM) anti-SARS-CoV2 activity.5
分子式:C24H38N2O·2HCl
分子量:443.50
溶剂:DMSO (>25 mg/ml) Water (5 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):High affinity sigma 2 ligand / Anti-SARS-COV2
Function / Pharmacology:PB28 is a very potent high affinity (Ki = 5.3 nM1, 0.34 nM2) sigma 2 agonist. Selective for sigma 2 over sigma1 (approx 30-40x).1,2 PB28 inhibited cell growth in MCF7 and MCF7 ADR breast cancer cells and displayed strong synergism with doxorubicin.3 PB28 potently inhibited Kv2.1 currents in a sigma-independent manner.4 PB28 was recently found to have potent (IC50 = 280 nM) anti-SARS-CoV2 activity.5
