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R428
- 英文名称：R428
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11356
- cas：1037624-75-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11356 |
| 用途 | 科研检测 |
| 英文名称 | R428 |
| 包装规格 | 1MG |
| CAS编号 | 1037624-75-1 |
| 别名 | R428 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C30H34N8
分子量:506.64
溶剂:DMSO (>25 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):AXL inhibitor
Function / Pharmacology:R428 (1037624-75-1) is a potent and selective inhibitor of AXL kinase (IC50 = 1.4nM).1 R428 has been shown to overcome chemotherapy resistance to various agents in multiple cancer models.2-5 AXL has been shown to suppress myeloid cell activation and function – combined AXL inhibition with R428 and PD-1 blockade showed potent synergistic antitumor effects.6,7
分子式:C30H34N8
分子量:506.64
溶剂:DMSO (>25 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):AXL inhibitor
Function / Pharmacology:R428 (1037624-75-1) is a potent and selective inhibitor of AXL kinase (IC50 = 1.4nM).1 R428 has been shown to overcome chemotherapy resistance to various agents in multiple cancer models.2-5 AXL has been shown to suppress myeloid cell activation and function – combined AXL inhibition with R428 and PD-1 blockade showed potent synergistic antitumor effects.6,7
