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NG52
- 英文名称：NG52
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11361
- cas：212779-48-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11361 |
| 用途 | 科研检测 |
| 英文名称 | NG52 |
| 包装规格 | 1MG |
| CAS编号 | 212779-48-1 |
| 别名 | NG52 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C16H19ClN6O
分子量:346.82
溶剂:DMSO (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Phosphoglycerate kinase 1 inhibitor
Function / Pharmacology:Inhibitor of Cdc2-cyclin B (IC50 = 340 nM) as well as Cdc28p (IC50 = 7 μM) and Pho85p (IC50 = 2 μM).1 It inhibited phosphoglycerate kinase 1 (IC50 = 2.5 μM) and inhibited the proliferation of glioma U87 and U251 cell lines via reversal of the Warburg effect.2 NG52 inhibited the proliferation, increased apoptosis, and reduced the migration and invasive ability of OVCAR3 and ES-2 ovarian cancer cell lines via suppression of glycolytic capability.3
分子式:C16H19ClN6O
分子量:346.82
溶剂:DMSO (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Phosphoglycerate kinase 1 inhibitor
Function / Pharmacology:Inhibitor of Cdc2-cyclin B (IC50 = 340 nM) as well as Cdc28p (IC50 = 7 μM) and Pho85p (IC50 = 2 μM).1 It inhibited phosphoglycerate kinase 1 (IC50 = 2.5 μM) and inhibited the proliferation of glioma U87 and U251 cell lines via reversal of the Warburg effect.2 NG52 inhibited the proliferation, increased apoptosis, and reduced the migration and invasive ability of OVCAR3 and ES-2 ovarian cancer cell lines via suppression of glycolytic capability.3
