菜单 Close 公司首页 公司介绍 公司动态 证书荣誉 联系方式 在线留言
您当前的位置: 网站首页 > 产品展厅 >药物类 >Firsocostat
Firsocostat
  • 英文名称:Firsocostat
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B11373
  • cas:1434635-54-7
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-04-30
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B11373
用途 科研检测
英文名称 Firsocostat
包装规格 1MG
CAS编号 1434635-54-7
别名 Firsocostat
纯度 98+%
分子式
是否进口
纯度:98% by HPLC,;NMR (Conforms)
分子式:C28H31N3O8S
分子量:569.63
溶剂:DMSO (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Allosteric acetyl-CoA carboxylase inhibitor
Function / Pharmacology:Potent (IC50 = 1.7 nM ACC1; 2.6 nM ACC2) allosteric protein-protein interaction inhibitor of acetyl-CoA carboxylase (ACC).1 It interacts with the ACC phosphopeptide acceptor and dimerization site to inhibit enzymatic activity resulting in decreased fatty acid synthesis and stimulation of fatty acid oxidation. It reduced hepatic steatosis, improves insulin sensitivity, reduces weight gain, and favorably affects dyslipidemia in rats. Firsocostat decreased hepatic steatosis and fibrosis markers in patients with nonalcoholic fatty liver disease.2 Directly impairs profibrinogenic activity of hepatic stellate cells (HSC) via prevention of induction of glycolysis and oxidative phosphorylation during HSC activation.3
联系方式
手机:15317051735
Q Q:
二维码扫描访问