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KC7F2
- 英文名称:KC7F2
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11377
- cas:927822-86-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-04-30
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11377 |
用途 | 科研检测 |
英文名称 | KC7F2 |
包装规格 | 1MG |
CAS编号 | 927822-86-4 |
别名 | KC7F2 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C16H16Cl4N2O4S4
分子量:570.38
溶剂:DMSO (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):HIF-1α inhibitor
Function / Pharmacology:KC7F2 is an inhibitor of HIF-1α (IC50 = 20 μM).1 It inhibited HIF-mediated transcription in cells derived from glioma, breast, and prostate cancers. The mechanism of action of KC7F2 is via down-regulation of HIF-1α protein synthesis accompanied by suppression of phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 and p70 S6 kinase, key regulators of HIF-1α protein synthesis.
分子式:C16H16Cl4N2O4S4
分子量:570.38
溶剂:DMSO (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):HIF-1α inhibitor
Function / Pharmacology:KC7F2 is an inhibitor of HIF-1α (IC50 = 20 μM).1 It inhibited HIF-mediated transcription in cells derived from glioma, breast, and prostate cancers. The mechanism of action of KC7F2 is via down-regulation of HIF-1α protein synthesis accompanied by suppression of phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 and p70 S6 kinase, key regulators of HIF-1α protein synthesis.