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BT2
- 英文名称：BT2
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11379
- cas：34576-94-8
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11379 |
| 用途 | 科研检测 |
| 英文名称 | BT2 |
| 包装规格 | 1MG |
| CAS编号 | 34576-94-8 |
| 别名 | BT2 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:95% by TLC;NMR (Conforms)
分子式:C9H4Cl2O2S
分子量:247.10
溶剂:DMSO (>20 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):BCKDC kinase inhibitor
Function / Pharmacology:BT2 is an inhibitor of the mitochondrial branched-chain α-ketoacid dehydrogenase complex kinase (BCKDC) - IC50 = 3.19 μM.1 Inhibition of this kinase has been shown to reduce levels of branched-chain amino acid concentrations in vivo. BT2 has also been shown to be a moderate inhibitor (Ki = 59 μM) of myeloid cell leukemia 1(Mcl 1), a Bcl-2 family protein.2
分子式:C9H4Cl2O2S
分子量:247.10
溶剂:DMSO (>20 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):BCKDC kinase inhibitor
Function / Pharmacology:BT2 is an inhibitor of the mitochondrial branched-chain α-ketoacid dehydrogenase complex kinase (BCKDC) - IC50 = 3.19 μM.1 Inhibition of this kinase has been shown to reduce levels of branched-chain amino acid concentrations in vivo. BT2 has also been shown to be a moderate inhibitor (Ki = 59 μM) of myeloid cell leukemia 1(Mcl 1), a Bcl-2 family protein.2
