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(R)-(+)Etomoxir Na
  • 英文名称:(R)-(+)Etomoxir Na
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B11382
  • cas:828934-41-4
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-23
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B11382
用途 科研检测
英文名称 (R)-(+)Etomoxir Na
包装规格 1MG
CAS编号 828934-41-4
别名 (R)-(+)Etomoxir Na
纯度 98+%
分子式
是否进口
纯度:98% by HPLC,;NMR (Conforms)
分子式:C15H18ClO4·Na
分子量:320.74
溶剂:DMSO (5 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Carnitine palmitoyltransferase inhibitor
Function / Pharmacology:Etomoxir (828934-41-4) is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1).1 It is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease2, diabetes3, and cancer4,5. Use of etomoxir in concentrations greater than 5 μM induces acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells indicating a loss of specificity for CTP1 at these concentrations.6 200 μM etomoxir inhibited complex I of the electron transport chain.7
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