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CB-103
- 英文名称：CB-103
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11383
- cas：218457-67-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-11-03
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11383 |
| 用途 | 科研检测 |
| 英文名称 | CB-103 |
| 包装规格 | 1MG |
| CAS编号 | 218457-67-1 |
| 别名 | CB-103 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C15H18N2O
分子量:242.32
溶剂:DMSO (>30 mg/ml)
性状:Off-white to pale orange solid
存储:RT
Activity (short version):Notch signaling pathway inhibitor
Function / Pharmacology:Orally active inhibitor of the Notch signaling activation complex (IC50’s from 0.9 to 3.9 μM in various cell-based assays), the most downstream level of the Notch signaling pathway. It inhibited the growth of Notch-addicted human T cell acute lymphoblastic leukemia cells as well as other cell lines. CB-103 also inhibited the growth of human breast cancer and leukemia xenografts without the intestinal toxicity associated with γ-secretase Notch inhibitors.
分子式:C15H18N2O
分子量:242.32
溶剂:DMSO (>30 mg/ml)
性状:Off-white to pale orange solid
存储:RT
Activity (short version):Notch signaling pathway inhibitor
Function / Pharmacology:Orally active inhibitor of the Notch signaling activation complex (IC50’s from 0.9 to 3.9 μM in various cell-based assays), the most downstream level of the Notch signaling pathway. It inhibited the growth of Notch-addicted human T cell acute lymphoblastic leukemia cells as well as other cell lines. CB-103 also inhibited the growth of human breast cancer and leukemia xenografts without the intestinal toxicity associated with γ-secretase Notch inhibitors.
