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MOMIPP
  • 英文名称:MOMIPP
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B11397
  • cas:1363421-46-8
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-04-30
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B11397
用途 科研检测
英文名称 MOMIPP
包装规格 1MG
CAS编号 1363421-46-8
别名 MOMIPP
纯度 98+%
分子式
是否进口
纯度:98% by TLC;NMR (Conforms)
分子式:C18H16N2O2
分子量:292.33
溶剂:DMSO (7 mg/ml)
性状:Orange solid
存储:-20°C
Activity (short version):Methuosis inducer
Function / Pharmacology:MOMIPP is an inducer of Methuosis, a novel form of nonapoptotic cell death.1 Methuosis is characterized by fusion of macropinocytotic vesiscles into progressively larger vacuoles resulting in a decrease in metabolic activity and rupture of the cell membrane.2 MOMIPP was able to effectively reduce the growth and viability of Temozolomide-resistant glioblastoma and doxorubicin-resistant breast cancer cells at low micromolar concentrations. MOMMIP has also been shown to disrupt vesicular trafficking at the lysosomal nexus resulting in impaired degradation of EGF and LDL receptors, defective processing of procathepsins and accumulation of autophagosomes.3
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