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AZ3146
- 英文名称：AZ3146
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11399
- cas：1124329-14-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-06-21
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11399 |
| 用途 | 科研检测 |
| 英文名称 | AZ3146 |
| 包装规格 | 1MG |
| CAS编号 | 1124329-14-1 |
| 别名 | AZ3146 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C24H32N6O3S2
分子量:452.56
溶剂:DMSO (10 mg/ml) Eathnaol (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Msp1 kinase inhibitor
Function / Pharmacology:AZ3146 is a potent (IC50 = 35 nM) and selective monopolar spindle 1 (Mps1/TTK) kinase inhibitor.1 Mps1 has an essential role in the spindle assembly checkpoint, an inhibitory network that restrains anaphase until all kinetochores are stably attached to spindle microtubules during mitosis. AZ3146 decreased hepatocellular carcinoma growth in vitro (SMMC-7721 and BEL-7404 cells).2
分子式:C24H32N6O3S2
分子量:452.56
溶剂:DMSO (10 mg/ml) Eathnaol (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Msp1 kinase inhibitor
Function / Pharmacology:AZ3146 is a potent (IC50 = 35 nM) and selective monopolar spindle 1 (Mps1/TTK) kinase inhibitor.1 Mps1 has an essential role in the spindle assembly checkpoint, an inhibitory network that restrains anaphase until all kinetochores are stably attached to spindle microtubules during mitosis. AZ3146 decreased hepatocellular carcinoma growth in vitro (SMMC-7721 and BEL-7404 cells).2
